When doctors need to confirm an Alzheimer’s diagnosis, they often turn to a combination of brain imaging and cell analysis. Both have their downsides. The latter involves a lumbar puncture, an invasive and painful procedure that’s more commonly known as a spinal tap. A doctor will insert a needle into the lower back to extract a sample of the patient’s cerebrospinal fluid. A lab technician then tests the sample for signs of progressive nerve cell loss and excessive amyloid and tau protein accumulation. MRI scans are less invasive but they’re often expensive and accessibility is an issue; not every community has access to the technology.
The next best tool for diagnosing Alzheimer’s disease is a blood test. While some can detect abnormal tau protein counts, they’re less effective at spotting the telltale signs of neurodegeneration. But that could soon change. This week, in the journal Brain, a multinational team made up of researchers from Sweden, Italy, the UK and US detailed a new antibody-based blood test they recently developed. The new test can detect brain-derived tau proteins, which are specific to Alzheimer’s disease. Following a study of 600 patients, the team found their test could reliably distinguish the illness from other neurodegenerative diseases.
Dr. Thomas Karikari, a professor of psychiatry at the University of Pittsburgh and one of the co-authors of the study, told The Guardian he hopes the breakthrough could help other researchers design better clinical trials for Alzheimer’s treatments. “A blood test is cheaper, safer and easier to administer, and it can improve clinical confidence in diagnosing Alzheimer’s and selecting participants for clinical trial and disease monitoring,” he said. There’s more work to be done before the test makes its way to your local hospital. To start, the team needs to validate that it works for a wide variety of patients, including those who come from different ethnic backgrounds.
Today is Stan Lee’s 100th birthday and Marvel marked the occasion by revealing that a documentary about his life will hit Disney+ next year. Lee, who died in 2018, is a critical part of Marvel’s legacy. The many, many characters he’s credited with co-creating include Spider-Man, Iron Man, Black Panther, Ant-Man, X-Men, The Fantastic Four and The Incredible Hulk.
Marvel didn’t reveal many details about the project, though it did release a teaser containing some of Lee’s cameos in Marvel Cinematic Universe movies. It’s unclear whether the documentary will take a warts-and-all look at Lee’s complex life or who will be involved in telling his story.
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Whether you just got your hands on a new phone or want to give your current device a makeover, the easiest way to make the most of your smartphone is to try out new apps. The tricky part is not going overboard and installing too many. Below you’ll find a dozen of the best smartphones apps we think you should try.
Bitwarden
Bitwarden
If you only take one piece of advice away from this article, it’s that you should download a password manager. If you’ve never used one before, it’s hard to go wrong with Bitwarden. It won’t wow you with beautifully designed apps, but you’ll appreciate its fair business model. The best part of the Bitwarden experience is that all of its core features are free to use. Without paying a cent, you can use Bitwarden on as many devices as you want. By comparison, LastPass charges $3 per month for that same functionality. If you want to support Bitwarden, the $10 per year Premium plan is well worth the money as you get access to features like advanced two-factor authentication.
FireFox
Firefox
If it’s been a few years since you last used Firefox, now is a great time to revisit it. Partway through last year, Mozilla overhauled the Android version of its browser to bring over many of its best desktop features to mobile. That release saw Mozilla add more robust support for third-party add-ons. It also brought over its Enhanced Tracking Protection feature, which stops trackers from misusing your browsing data. Separately, with Apple allowing you to change your default browser since the release of iOS 14, there’s never been a better time for iPhone users to liberate themselves from Safari.
Headspace
Headspace
I subscribed to Headspace at the start of the pandemic. Since then, it’s become one of the few apps I use every day. Yes, Headspace is a meditation and mindfulness app, but it’s also so much more than that. You’ll find it also has a mix of music designed to help you focus and workouts for unwinding at the end of a long day. Across the board, everything it offers is excellent, and you’ll find yourself turning to it for more than just peace of mind.
Notion
Notion
Notion is one of the most powerful productivity tools you can download right now, and if your goal for 2023 is to organize your personal and professional lives, I can’t recommend it enough. What makes Notion so powerful is an interface that looks simple but offers a lot of flexibility. I’ve used Notion to create to-do lists, write notes and features and manage personal projects. It can be a bit overwhelming at first. My suggestion is to head over to YouTube to see how other people have used Notion’s features to organize their lives.
Libby
Libby
If you want to do more reading in 2022, forget about buying books through Amazon and download Libby instead. If you’re not familiar with the app, it allows you to borrow ebooks, digital magazines and graphic novels from your local library. All you need is a library card, which most systems across the US offer for free. Sometimes you have to wait to borrow the books you want to read most, but you’ll find Libby will dramatically expand your reading list.
Transit
Transit
There’s nothing worse than waiting for a bus on a cold winter’s day or watching three go by one after another. Avoid both situations with one of the best public transit planning apps on Android and iOS. Transit excels where other apps in the category fail thanks to its clean, easy-to-use interface that highlights all the options near you. It also has one of the better algorithms for predicting departure times, so you’ll know exactly when you need to run out of your house or apartment to catch the next bus, train or streetcar.
Paprika
Paprika
Paprika is the best $5 you can spend to make feeding yourself even easier. At its core, it allows you to download recipes from your favorite websites and make them accessible on all your devices. You can also use it to scale the size of the meal you’re about to cook and convert between metric and imperial measurements. Add to that a meal planner, shopping lists and a tool for tracking the ingredients in your pantry, and you have an indispensable app for home cooks.
Pocket Casts
Pocket Casts
With podcasts becoming ever more popular with each passing year, there’s a good chance you already have a handful of favorite shows you listen to every week. As much as Spotify would like to convince you it has the best podcast app, that distinction goes to Pocket Casts. We like it because it offers a consistently great experience across every system it supports. And if you use a mix of platforms from Apple, Google and Microsoft, you don’t have to worry about syncing, either. It’s also nice to use software that doesn’t feel caught between two worlds in the way that Spotify does. Pocket Casts isn’t trying to be anything more than an app for listening to podcasts. That’s not something you can say of Spotify, and it’s often a source of frustration for those who turn to it for music.
Pocket
Pocket
Another way to read more in 2022 is to download Pocket. It’s among the most popular read-it-later apps out there, allowing you to save articles you find online. Much like Pocket Casts, what makes this app compelling is that it offers a consistently excellent device-agnostic experience, making it a great option for those who haven’t gone all-in on one ecosystem. Whether you use Chrome, Safari or Edge, you can install a browser extension to save articles you stumble upon. You can then read them later without distractions on your phone or tablet. Just don’t forget to make a dent in your Pocket reading list occasionally.
Signal
Signal
We understand, asking your friends and family to install another messaging app on their phone can sometimes feel like a Sisyphean task, but the effort has also never been more worth it. In Signal, you’ll find one of the most secure chat apps on the market. It has all the features you would expect from a messaging program, including support for stickers and Snapchat-like Stories, but more important are the ways Signal is different from rivals like WhatsApp and Telegram. Signal is a nonprofit and is one of the few apps committed to privacy rather than revenue via data collection. That means you won’t see any ads in the app, nor will the company sell your data to third-party marketers.
Tunnelbear
Tunnelbear
After a Password manager, one of the best tools you can use to safeguard your online privacy is a VPN. Again, there are many options out there, but we like TunnelBear for its simplicity and whimsical ursine theme. A VPN isn’t as essential as a password manager, but you’ll want to get one if you frequently find yourself traveling or using the public WiFi at places like cafes and libraries. Using a VPN in those contexts will ensure your connection is protected with encryption so that any information you send over remains safe and private.
Snapseed
Snapseed
Most recent phones come with great cameras. Still, even with the latest iPhone, Samsung Galaxy or Google Pixel, almost every photo can benefit from an edit before you share it. The options you have for photo editing apps are nearly endless, but if you want something that works well, look no further than Snapseed. It’s an old favorite that offers a comprehensive suite of editing options but never gets bogged down in too many sliders and dials. Best of all, it makes it easy to save edits to your camera roll and upload them to apps like Instagram.
Health company Movano has teased its first smart ring, the Evie, designed for health, fitness and cycle tracking. It looks like a rival to Oura’s latest smart ring and other health-tracking wearables, though the company says it’s “designed uniquely for women.” Movano plans to provide a closer look next week at CES 2023.
The ring made its debut at CES 2022 with no name and a similar design, but Movano has since changed course on price and other factors. It will sell the ring sometime in 2023 at a one-time price below $300 (there’s no exact date or price yet), rather than using a subscription model as it said last year.
It offers many of the health metrics seen on Oura’s ring and wearables from Apple and others. It can measure heart rate, blood-oxygen, skin temperature variability, steps, calories, sleep, period and ovulation tracking, and more. Wearers will can get advice from health experts inside the app and it will meet medical device manufacturing standards, the company promised.
“As a medical device, Evie will go beyond the status quo of other wearables on the market,” said Movano CEO John Mastrototaro. “We are bringing together medical grade biometric data and insights in a comfortable and contemporary wearable.”
With the ability to measure steps, calories burned and specific activities, Evie can also be used as a fitness tracker. However, it’s primary purpose is to give a picture of overall health, “turning biometric data into actionable insights,” Movano wrote in the press release.
The company also promises security and privacy when transferring data to the cloud or health providers. It’s currently seeking all-important FDA clearance, which will dictate the release date. If that takes too long, though, it may come to market as a wellness device at first. The Evie smart ring will only be released in the US to start with, but may come to other markets later — we should learn more about it next week at CES 2023.
German researchers who purchased biometric capture devices on eBay found sensitive US military data stored on the machine’s memory cards. According to The New York Times, that included fingerprints, iris scans, even photographs, names and descriptions of the individuals, mostly from Iraq and Afghanistan. Many individuals worked with the US army and could be targeted if the devices fell into the wrong hands, according to the report. One device was purchased at a military auction, and the seller said they were unaware that it contained sensitive data. There was an easy solution too: The US military could have eliminated the risk by simply removing or destroying the memory cards before selling them.
Workers at Proletariat, a Boston-based studio Blizzard bought earlier this year, announced they recently filed for a union election with the National Labor Relations Board (NLRB). Proletariat is the third Activision Blizzard studio to announce a union drive in 2022. However, past campaigns at Raven Software and Blizzard Albany involved the quality assurance workers at those studios – the effort at Proletariat includes all non-management workers. The employees at Proletariat say they aim to preserve the studio’s “progressive, human-first” benefits, including its flexible paid time off policy and robust healthcare options. Additionally, they want to protect the studio from crunch – compulsory overtime during game development.
LG is taking a more minimalist approach to its kitchen appliances in 2023, with less showy profiles, colors and, seemingly, controls. While we’re not getting a close-up look at all the dials and buttons yet, the appliances look restrained compared to previous years’ models. In the past, we’ve seen a washing machine whose flagship feature was an entire extra washing machine. There was also a dryer that had two doors. Just because. LG says it’s used recycled materials across multiple machine parts, adding that its latest appliances also require fewer total parts and less energy than typical kitchen appliances. This would dovetail with the company’s announcements at the start of the year, where LG said it would offer upgradability for its home appliances. So far, that’s included new filters for certain use cases and software upgrades with new washing programs for laundry machines.
Lawmakers and staff members who have TikTok on their phones would have to delete it.
TikTok is now banned on any device owned and managed by the US House of Representatives, according to Reuters. The House’s Chief Administrative Officer (CAO) reportedly told all lawmakers and their staff in an email that they must delete the app from their devices, because it’s considered “high risk due to a number of security issues.” Further still, everyone detected to have the social networking application on their phones would be contacted to make sure it’s deleted.
LG may not make smartphones anymore, but it’s still building components for them. The company’s LG Innotek arm just unveiled a periscope-style true optical zoom camera module with a 4-9 times telephoto range. Most smartphone cameras use hybrid zoom setups that combine certain zoom ranges (typically 2x, 3x, 10x, etc.) with a digital zoom to fill in between those (2.5x, 4.5x, etc.), leading to reduced detail. LG’s “Optical Zoom Camera,” however, contains a zoom actuator with movable components, like a mirrorless or DSLR camera. That would help retain full image quality through the entire zoom range, while potentially reducing the size and number of modules required. Could this mean the death of the camera bump?
