FDA clears Wandercraft’s exoskeleton for stroke patient rehab

Stroke patients in the US could soon take advantage of cutting-edge robotics during the recovery process. The Food and Drug Administration has cleared Wandercraft’s Atalante exoskeleton for use in stroke rehabilitation. The machine can help with intensive gait training, particularly for people with limited upper body mobility that might prevent using other methods.

The current-generation Atalante is a self-balancing, battery-powered device with an adjustable gait that can help with early steps through to more natural walking later in therapy. While the hardware still needs to be used in a clinical setting with help from a therapist, its hands-free use lets patients reestablish their gait whether or not they can use their arms.

Wandercraft plans to deliver its first exoskeletons to the US during the first quarter of the year, though it didn’t name initial customers. It only recently launched its commercial business in the country, but financial backer Quadrant Management says Wandercraft could “significantly scale” its operations within the next one to two years.

FDA-cleared exoskeletons are still relatively rare, and are still limited to helping with specific conditions. Last June, Ekso Bionics received permission to market its EksoNR device for multiple sclerosis rehab. Wandercraft’s approval makes the technology accessible for a wider range of patients, and may be especially helpful when strokes are a major cause of long-term disability in the US. Over 795,000 people have a stroke in the country each year — this could help some of them regain freedom of movement.

There was a lot of pee on the CES 2023 show floor

One swallow doesn’t make a summer, and I’m not sure if you can count four instances of a product as a trend, but it’s certainly an interesting thread at this year’s CES. At this year’s show, a quartet of companies are showing off urine analysis tools d…

The Morning After: The winners and losers in tech this year

As we approach the end of the year, it’s time for Engadget to wrap up the successes and failures in tech from the last twelve months. While it might be easier point out the messes made by the likes of crypto, Google’s Stadia cloud gaming platform and, ugh, Twitter, there were some highlights too. These include the eventual arrival of Steam’s handheld gaming PC, all those Wordle options, and some dazzling new views of space. The worst of 2022 centers an awful lot on tech bros, if you hadn’t rolled your eyes at them enough in the preceding years. From the collapse of FTX to the precarious state of Twitter, it’s been a mess. Meanwhile, the likes of Peloton have struggled to hold onto their pandemic user base, and Toyota’s EV efforts haven’t been great. Check out all our hits and our misses of 2022.

– Mat Smith

The Morning After isn’t just a newsletter – it’s also a daily podcast. Get our daily audio briefings, Monday through Friday, by subscribing right here.

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Amazon might be making a standalone sports streaming app

No word yet on when the company expects to launch the service.

A report from The Information says that Amazon is working on a new standalone streaming app to declutter Prime Video and better highlight its deals with the NFL, the UK’s Premier League and New York Yankees. The development follows recent comments from Amazon CEO Andy Jassy, who highlighted live sports content as one of the areas where the company plans to continue spending money even as it cuts costs in other areas. The Information says it doesn’t know when Amazon might release the app, nor if the company plans to charge separately for access to Prime Video’s sports content. The outlet also notes Amazon may decide to shelve the app. Amazon did not immediately respond to Engadget’s comment request. Earlier this month, Google reportedly agreed to pay between $2.1 billion and $2.2 billion for the NFL’s Sunday Ticket package.

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The Evie is a smart ring designed ‘for women’

It can measure heart rate, clinical SpO2, skin temperature variability and more.

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Evie

Health company Movano has teased its first smart ring, the Evie, designed for health, fitness and cycle tracking. It looks like a rival to Oura’s latest smart ring, though the company says it’s “designed uniquely for women.” It offers many of the health metrics seen on Oura’s ring and wearables from Apple and others. It can measure heart rate, blood-oxygen, skin temperature variability, steps, calories, sleep, period and ovulation tracking, and more. Movano plans to provide a closer look next week at CES 2023.

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A Stan Lee documentary will hit Disney+ next year

Marvel announced the news on Lee’s 100th birthday.

Yesterday was Marvel legend Stan Lee’s 100th birthday and the comic giant marked the occasion by revealing that a documentary about his life will hit Disney+ next year. Lee, who died in 2018, is a critical part of Marvel’s legacy. The many, many characters he’s credited with co-creating include Spider-Man, Iron Man, Black Panther, Ant-Man, X-Men, The Fantastic Four and The Incredible Hulk. Disney has mined its history for several documentary projects for its streaming service. When Disney+ debuted three years ago, it featured a docuseries on the Imagineers, the minds behind its theme parks.

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Researchers develop blood test that can reliably detect Alzheimer’s disease

The test could replace lumbar punctures and brain scans.

When doctors need to confirm an Alzheimer’s diagnosis, alongside brain scans, it can involve a lumbar puncture – an invasive and painful procedure that’s more commonly known as a spinal tap. The next best tool for diagnosing Alzheimer’s disease is a blood test. While some tests can detect abnormal tau protein counts as a possible indicator of Alzheimer’s disease, they’re less effective at spotting the telltale signs of neurodegeneration. But this week, in the journal Brain, a multinational team of researchers from Sweden, Italy, the UK and US detailed a new antibody-based blood test that can detect brain-derived tau proteins specific to Alzheimer’s disease. Following a study of 600 patients, the team found their test could reliably distinguish the illness from other neurodegenerative diseases.

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Researchers develop blood test that can reliably detect Alzheimer’s disease

When doctors need to confirm an Alzheimer’s diagnosis, they often turn to a combination of brain imaging and cell analysis. Both have their downsides. The latter involves a lumbar puncture, an invasive and painful procedure that’s more commonly known as a spinal tap. A doctor will insert a needle into the lower back to extract a sample of the patient’s cerebrospinal fluid. A lab technician then tests the sample for signs of progressive nerve cell loss and excessive amyloid and tau protein accumulation. MRI scans are less invasive but they’re often expensive and accessibility is an issue; not every community has access to the technology.

The next best tool for diagnosing Alzheimer’s disease is a blood test. While some can detect abnormal tau protein counts, they’re less effective at spotting the telltale signs of neurodegeneration. But that could soon change. This week, in the journal Brain, a multinational team made up of researchers from Sweden, Italy, the UK and US detailed a new antibody-based blood test they recently developed. The new test can detect brain-derived tau proteins, which are specific to Alzheimer’s disease. Following a study of 600 patients, the team found their test could reliably distinguish the illness from other neurodegenerative diseases.

Dr. Thomas Karikari, a professor of psychiatry at the University of Pittsburgh and one of the co-authors of the study, told The Guardian he hopes the breakthrough could help other researchers design better clinical trials for Alzheimer’s treatments. “A blood test is cheaper, safer and easier to administer, and it can improve clinical confidence in diagnosing Alzheimer’s and selecting participants for clinical trial and disease monitoring,” he said. There’s more work to be done before the test makes its way to your local hospital. To start, the team needs to validate that it works for a wide variety of patients, including those who come from different ethnic backgrounds.