A 17-year neuroimaging study of persons diagnosed with depression as children found differences in white matter in the dorsal cingulum bundle region of the brain compared to persons without depression of similar age. The emergence of these differences was first detected in adolescence. The study was published in Depression and Anxiety. Depression, or major depressive disorder (MDD), as it is officially called, is one of the most common major mental disorders and a leading cause of disability. Symptoms include diminished interest or pleasure in activities most of the day, changes in appetite re…